Peer Reviewed Publications

R. Sinkus, B.E. Van Beers, V. Vilgrain, N. DeSouza, J.C. WatertonApparent diffusion coefficient from magnetic resonance imaging as a biomarker in oncology drug development.European Journal of Cancer2012484425-431
D. Soloviev, D. Lewis, D. Honess, E. Aboagye[18F]FLT: An imaging biomarker of tumour proliferation for assessment of tumour response to treatment.European Journal of Cancer2012484416-424
Q. Nguyen, A. Challapalli , G. Smith , R. Fortt, E.O. AboagyeImaging apoptosis with positron emission tomography: ‘Bench to bedside’ development of the caspase-3/7 specific radiotracer [18F]ICMT-11.European Journal of Cancer2012484432-440
J.C. Waterton, L. PylkkaanenQualification of imaging biomarkers for oncology drug development.European Journal of Cancer2012484409-415
P. Lambin, E. Rios-Velazquez, R. Leijenaar, S. Carvalho, R. GPM van Stiphout, P. Granton, C. ML Zegers, R. Gillies, R. Boellard, A. Dekker, H. JWL AertsRadiomics: Extracting more information from medical images using advanced feature analysis.European Journal of Cancer2012484441-446
M.-C. Asselin, J. PB O’Connor, R. Boellaard, N. A Thacker, A. JacksonQuantifying heterogeneity in human tumours using MRI and PET.European Journal of Cancer2012484447-455
V. Frings, A.J. de Langen, M. Yaqub, R.C. Schuit,
A.A.M. van der Veldt, O.S. Hoekstra, E.F. Smit, R. Boellaard
Methodological Considerations in Quantification
of 3'-Deoxy-3'-[18F]Fluorothymidine Uptake
Measured with Positron Emission Tomography
in Patients with Non-Small Cell Lung Cancer
Molecular Imaging and Biology2013
R.T.H. Leijenaar, S. Carvalho, E. Rios Velazquez, W.J.C. van Elmpt, C. Parmar, O.S. Hoekstra, C.J. Hoekstra, R. Boellaard, A.L.A.J. Dekker, R.J. Gillies, H.J.W.L. Aerts, P. LambinStability of FDG-PET Radiomics features: an integrated analysis of test-retest and inter-observer variability
Acta Oncologica2013521391-1397
S. Carvalho, R.T.H. Leijenaar, E. Rios Velazquez, C. Oberije, C. Parmar, W. van Elmpt, B. Reymen, E..G.C. Troost, M. Oellers, A. Dekker, R. Gillies, H.J.W.L. Aerts, P. LambinPrognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer.
Acta Oncologica2013521398-1404
P. Lambin, E. Roelofs, B. Reymen, E. Rios Velazquez, J. Buijsen, K. Zegers, S. Carvalho, R. Leijenaar, G. Nalbantov, C. Oberije, M. Scott Marshall, F. Hoebers, E.G.C. Troost, R.G.P.M. van Stiphout, W. van Elmpt, T. van der Weijden, L. Boersma, V. Valentini, A. Dekker‘Rapid Learning health care in oncology’ – An approach towards decision support systems enabling customised radiotherapy’.Radiotherapy and Oncology2013
V. Frings, A.A. van der Veldt, R. Boellaard, G.J. Herder, E. Giovannetti, R. Honeywell, G.J. Peters, E. Thunnissen, O.S. Hoekstra, E.F. SmitPemetrexed induced thymidylate synthase inhibition in non-small cell lung cancer patients: a pilot study with 3'-deoxy-3'-[¹⁸F]fluorothymidine positron emission tomography.PLoS One201385e63705
L. Bernardin, N. Hogg, D. Collins, S. Giles, E. O’Flynn, M. Orton, N.M. deSouzaDiffusion weighted magnetic resonance imaging for assessment of lung lesions: repeatability of the apparent diffusion coefficient measurementEuropean Radiology (in press)
H. Ragheb, N.A. Thacker, D.M. Morris, N.H.M. Hogg, A. JacksonIce-Water Phantom Localisation for Diffusion Calibration.Medical Image Understanding and Analysis (MIUA), Swansea University, Swansea, UK2012179-184
J.C. Waterton, D. LacombeQuIC-ConCePT: Quantitative imaging in oncology-connecting cellular processes to therapy.European Journal of Cancer20124874
Starmans M.H., Pintilie M., John T., Der S.D., Shepherd F.A., Jurisica I., Lambin P., Tsao M.S., Boutros P.C.Exploiting the noise: improving biomarkers with ensembles of data analysis methodologies.Genome Medicine201241184
Rios Velazquez E., Aerts H.J., Gu Y., Goldgof D.B., De Ruysscher D., Dekker A., Korn R., Gillies R.J., Lambin P.A semiautomatic CT-based ensemble segmentation of lung tumors: Comparison with oncologists' delineations and with the surgical specimen.Radiotherapy & Oncology20121052167-173
van der Heide U.A., Houweling A.C., Groenendaal G., Beets-Tan R.G., Lambin P.Functional MRI for radiotherapy dose painting.Magnetic Resonance Imaging20123091216-1223
Lambin P., van Stiphout R.G., Starmans M.H., Rios-Velazquez E., Nalbantov G., Aerts H.J., Roelofs E., van Elmpt W., Boutros P.C., Granone P., Valentini V., Begg A.C., De Ruysscher D., Dekker A.Predicting outcomes in radiation oncology-multifactorial decision support systems.Nature Reviews Clinical Oncology201310127-40
Carvalho S., Leijenaar R.T., Velazquez E.R., Oberije C., Parmar C., van Elmpt W., Reymen B., Troost E.G., Oellers M., Dekker A., Gillies R., Aerts H.J., Lambin P.Prognostic value of metabolic metrics extracted from baseline positron emission tomography images in non-small cell lung cancer.Acta Oncologica20135271398-1404
E. Roelofs, L. Persoon, S. Nijsten, W. Wiessler, A. Dekker, P. LambinBenefits of a clinical data warehouse with data mining tools to collect data for a radiotherapy trial.Radiotherapy & Oncology20131081174-179
Leijenaar R.T., Carvalho S., Velazquez E.R., van Elmpt W.J., Parmar C., Hoekstra O.S., Hoekstra C.J., Boellaard R., Dekker A.L., Gillies R.J., Aerts H.J., Lambin P.Stability of FDG-PET Radiomics features: An integrated analysis of test-retest and inter-observer variability.Acta Oncologica20135271391-1397

IMI oncology projects