J.C. WatertonReducing Attrition Rates in Anticancer Drug Discovery and Development: IMI Approaches2012
Sonja Schelhaas, Lydia Wachsmuth, Thomas Viel, Davina J. Honess, Kathrin Heinzmann, 3Donna-Michelle Smith, Sven Hermann, Stefan Wagner, Michael T. Kuhlmann, Carsten Müller-Tidow, Klaus Kopka, Michael Schäfers, Richard Schneider, Eric O. Aboagye, John Griffiths, Cornelius Faber, Andreas H. JacobsVariability of proliferation and diffusion in different
lung cancer models as measured by 18F-FLT-PET and DW-MRI
Kathrin Heinzmann, Dominick McIntyre, Davina Honess, John GriffithsQualification of the Apparent Diffusion Coefficient (ADC) as a biomarker of treatment response in mice models for Pancreatic Ductal Adenocarcinoma (PDA)2013
Lieke HoyngQuantitative Imaging in cancer: connecting cellular processes with therapy: Data and Image Analysis2013
Lieke HoyngInterobserver variability of image derived input functions for noninvasive pharmacokinetic analysis of PET studies2014
Sandra Heskamp, Otto BoermanEarly response monitoring with diffusion weighted MRI and 18F-FLT PET after cytotoxic 5-FU treatment in a rat model for colorectal liver metastases2014
Sonja Schäfers, Lydia Wachsmuth, Thomas Viel, Kathrin Heinzmann, Davina Honess, Donna-Michelle Smith, Sven Hermann, Stefan Wagner, Carsten Müller-Tidow, Klaus Kopka, Michael Schäfers, Cornelius Faber, Andreas H. JacobsDifference of 18F-FLT uptake and DW-MRI in various lung carcinoma xenografts2013
Sonja Schäfers, Lydia Wachsmuth, Stefan Wagner, Sven Hermann, Thomas Viel, Carsten Müller-Tidow, Klaus Kopka, Michael Schäfers, Cornelius Faber, Andreas H. JacobsComparative analysis of FDG and FLT uptake in different lung carcinoma cell lines2013
Marianthi-Vasiliki Papoutsaki, Jessica M Winfield, Harold G Parkes, Michael Boss, Matthew R Orton, Nandita M deSouzaA simple, modular, polyvinylpyrrolidone temperature-controlled phantom for quantitative MR quality control2015
Sonja Schelhaas, Annelena Held, Thomas Viel, Sven Hermann, and Andreas H. JacobsEarly [18F]FLT PET Imaging is not Predictive for Later Therapy Outcome in Gemcitabine Treated Lung Cancer Xenografts2016
Sonja Schelhaas, Annelena Held, Nicole Bäumer, Thomas Viel, Sven Hermann, Carsten Müller-Tidow, and Andreas H. Jacobs[18F]FLT PET Visualizes Recovery of Hematopoietic Organs in Mice after Therapy with the Myelosuppressive Agent Gemcitabine2016
Marianthi-Vasiliki Papoutsaki, Alex Weller, Nandita M de Souza, Matthew R OrtonEvaluation of inter-vendor sequence variations for the reliable estimation of the apparent diffusion coefficient of lung lesions2016
Ryan Pathak, Neil A Thacker, David M Morris, Philippe Garteiser, Sabrina Doblas, Bernard Van Beers, Houshang Amiri, Arend Heerschap, and Alan JacksonLiver metastasis from colorectal cancer; a comparison of reproducibility of ADC between multiple sites and vendors, at 1.5 T and 3 T2016
M-V Papoutsaki, A Weller, N M de Souza, D Collins, M R OrtonA method for assessing the signal to noise ratio of lung lesions in Diffusion Weighted MRI’2016
G.M. Kramer, V. Frings, D. Heijtel, E.F. Smit, O.S. Hoekstra, R. Boellaard, QuIC-ConCePT ConsortiumAccuracy and precision of parametric analysis of dynamic [18F]FLT PET in EGFR-mutated NSCLC patients.2016
Jean-Marie Guyader, Wyke Huizinga, Valerio Fortunati, Dirk H. Poot, Matthijs van Kranenburg, Jifke F. Veenland, Margarethus M. Paulides, Wiro J. Niessen, Stefan KleinTotal correlation-based groupwise image registration for quantitative MRI2016

IMI oncology projects